Bucklosan Tablets

Baklosan - a muscle relaxant that alters the transmission of neuromuscular impulses.

It is used to reduce hypertonicity of striated muscles, getting rid of muscle spasms in diseases of the central nervous system.

On this page you will find all the information about Baklosan: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Baklosan. Want to leave your opinion? Please write in the comments.

Clinico-pharmacological group

A muscle relaxant centrally acting.

Pharmacy sales terms

It is released on prescription.

Prices

How much is Amaryl? The average price in pharmacies is about 300 rubles.

Release form and composition

Baklosan is a biconvex, round, with a dividing strip of white tablets. 50 such tablets in a polypropylene can, one such can in a paper bundle.

  • One tablet of the drug contains 25 mg or 10 mg of baclofen as an active substance.
  • Excipients: lactose, gelatin, potato starch, magnesium stearate, talc, ethyl cellulose.

Pharmacological effect

The drug belongs to the group of centrally acting muscle relaxants, is an agonist of GABAB-receptors. Baklosan by reducing the excitability of the terminal parts of the sensory afferent fibers and suppressing the intermediate neurons inhibits the poly-and monosynaptic transmission of nerve impulses; reduces prestress of muscle spindles.

  • Baklosan has no effect on the transmission of nerve impulses in the neuromuscular synapses.

Reduces clonic convulsions and painful cramps in neurological diseases that are accompanied by spasms of skeletal muscles. Contributes to the expansion of the range of available movements in the joints, facilitates the process of active and passive kinesitherapy (massage, exercise, manual therapy).

Indications for use

The main indications for the use of baclosan are the following diseases:

  • Meningitis;
  • Traumatic brain injury;
  • Multiple sclerosis (increased muscle tone);
  • Stroke;
  • Cerebral palsy;
  • Alcoholism (nervous disorders, affective states).

In addition, Baklosan tablets are prescribed for various diseases of the spinal cord.

Contraindications

Absolute contraindications to the use of Baklosan according to the instructions are:

  • Parkinson's disease;
  • Cramps;
  • Psychosis;
  • Hypersensitivity to the drug;
  • Chronic renal failure;
  • Epilepsy;
  • Pregnancy;
  • Lactation period (breastfeeding).

The use of Baklosan is justified only when there is an acute need for children under 12 years old and the elderly.

In addition, it is undesirable to prescribe Baklosan tablets according to the instructions in the case of atherosclerosis of cerebral vessels and ulcers (stomach and duodenum).

Use during pregnancy and lactation

Baklosan is contraindicated for use during pregnancy and lactation.

Instructions for use

The instructions for use indicate that Baklosan is inside, during meals.

Instructions for children:

  • Initial dose - 5 mg 3 times / day. If necessary, the dose can be carefully increased every 3 days by 5 mg until the onset of the therapeutic effect.
  • The following doses are generally recommended: in children from 3 to 6 years old - 20-30 mg / day, from 6 to 10 years old - 30-60 mg / day, in children over 10 years old, the maximum daily dose is 2.5 mg / kg body weight; The initial dose is 1.5-2 mg / kg body weight.
  • The abolition of the drug is carried out gradually (within 1-2 weeks).

Instructions for adults:

  • The initial dose is 5 mg 3 times / day, followed by increasing the dose every 3 days at 5 mg until the onset of the therapeutic effect (usually up to 30-75 mg / day). The maximum daily dose is 100 mg.
  • The final dose is set so that the decrease in muscle tone does not lead to excessive myasthenia and does not impair motor function. With hypersensitivity, the initial daily dose is 5-10 mg, followed by a slower increase.
  • In chronic renal failure and during hemodialysis, the daily dose is 5 mg.
  • Patients requiring high doses of baclofen (from 75 mg to 100 mg per day) should use the drug in tablets of 25 mg.
  • In patients older than 65 years, the dose should be increased with caution, due to the increased risk of side effects.

In the case of skipping the next dose should not take a double dose of the drug.

Side effects

The use of Baklosan can cause the following side effects:

  1. Allergic reactions: urticaria, skin rash.
  2. From vessels and heart: decrease in cordial emission, decrease in arterial pressure.
  3. On the part of the digestive system: abnormal stool, dyspepsia, vomiting, nausea, abdominal pain, decreased liver function, dysgeusia.
  4. Nervous system disorders: sedation, drowsiness, dizziness, asthenia, confusion, fatigue, gait disturbances, insomnia, extremity tremor. In some cases, development of depressive states, euphoria, ataxia, nightmares, dysarthria, hallucinations and nystagmus have also been noted.
  5. Others: respiratory depression, muscle pain, reduced visual acuity, accommodation paresis, excessive sweating. In addition, the development of polyuria, dysuria, enuresis, urinary retention, erectile dysfunction and a decrease in body temperature is possible.
  6. In some cases, it is possible to develop an increase in spasticity, which should be regarded as a paradoxical reaction to baclofen.

Unwanted effects tend to be transient in nature. The side effects of baclofen should be distinguished from the symptoms of the disease about which the therapy is carried out; in patients with concomitant epilepsy, baclofen should be administered without discontinuation of antiepileptic drugs.

Overdose

With an overdose of baclosan, manifestations such as nausea and vomiting may occur; hypotension; apathy or depression; paresthesias (loss of sensation in the limbs, numbness, goosebumps); muscle weakness and myalgia (muscle pain, swelling); dizziness, drowsiness; increased fatigue; dry mouth; convulsions; confusion, euphoria; gait disturbance; enuresis, urinary retention or dysuria (difficulty urinating); diarrhea or constipation; ataxia (impaired coordination of movements); hallucinations; nystagmus (involuntary movements of the eyeballs); limb tremor (involuntary muscle contractions); accommodation paresis (blurred vision due to damage to the nerves of the eye); decrease in seizure threshold.

With prolonged use of the drug has a violation of the kidneys. Taking excessive doses of this medication can provoke respiratory depression in patients, and even the onset of coma.

Special instructions

With long-term use may have impaired renal function. In some patients, muscle spasticity increases, as a paradoxical effect occurs. The drug is processed in the liver, therefore, for liver diseases or diabetes mellitus, the doctor must monitor the activity of hepatic transaminases, alkaline phosphatase, blood glucose.

Baklosan significantly enhances the negative effects of alcohol, so for the period of drug treatment should refrain from taking alcohol-containing beverages.

Drug interactions

When taken together with medicines that affect the central nervous system, the activity of the latter increases. Parallel administration with tricyclic antidepressants promotes muscle tone regression.

Synchronous reception of Baklosan and Carbidopa causes the appearance of hallucinations and confusion of consciousness.

Reviews

We picked up some reviews of people about the preparation of Baklosan:

  1. Irina. This is quite a dangerous drug, I do not understand why it is in pharmacies in the public domain. I had to treat some patients whose drug addiction began precisely because of Baklosan.
  2. Inga. My grandfather was prescribed this medication, as he was diagnosed with multiple sclerosis. I can not say that it was easier for him, he was constantly annoyed and capricious. Switched to another drug.
  3. Pauline. This is generally an interesting drug. It helps me about back pain, my father also drank from prostatitis, even without a smart-prosta was the result, my sister heals her hand. It seems that it is suitable for everyone in life.
  4. Athanasius. Prescribed medication after a head injury when fell off a motorcycle and went to the deviation. There were no consequences. The medicine is specific, you should not prescribe it yourself (and it will not work out, all according to a strict prescription), otherwise you can thunder in the Durkee or get hooked on the ban. And it helped me cope with problems, no complaints.

How to stop taking the drug? This is often a question asked by patients. If withdrawal syndrome has occurred as a result of the use of the drug in the recommended doses, then discontinuation should be made gradually over two weeks. If dependence has arisen as a result of unauthorized use of the drug to achieve a narcotic effect, then it is necessary to seek help from a narcologist.

Analogs

The main analogues of Baklosan are other medicines with baclofen and muscle relaxants of the central action. For example, Baclofen from the same Polpharma.

  • Mydocalm (manufacturer - Hungary) has a similar effect, is available in tablets and ampoules. It costs about 400 rubles for 30 tablets.
  • Israeli Tizanidine - up to 200 rubles.
  • Swiss rectal ampoules Lirezal production Novartis cost from 2 to 2.5 thousand rubles.
  • Swiss Sirdalud costs from 200 to 350 rubles for the same amount.
  • Indian Tizanil is on sale for 200-250 rubles.

Before using analogues consult your doctor.

Storage conditions and shelf life

Keep out of the reach of children. Store in a dry, dark place at a temperature not exceeding 25 degrees.

Shelf life 3 years.

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